Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 6/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LIG1 | P18858 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133173 | 0.82 | CSNK2A1 (0.35) | ADRA2AADRA2BADRA2CHTR2CHTR2A | |
| SCHEMBL6493951 | 0.80 | TDP1 (0.40) | TSHR | |
| SCHEMBL14721610 | 0.79 | THRA (0.32) | MAPK1 | |
| SCHEMBL8065205 | 0.79 | HTT (0.34) | — | |
| SCHEMBL1615176 | 0.79 | S1PR5 (0.36) | ADRA2AHPGDTSHRHTR2B | |
| SCHEMBL3159501 | 0.79 | S1PR5 (0.36) | ADRA2AHPGDTSHRHTR2B | |
| SCHEMBL8065187 | 0.77 | MEN1 (0.39) | HPGDMAPK1ALDH1A1 | |
| SCHEMBL1614837 | 0.77 | S1PR1 (0.32) | — | |
| SCHEMBL8080081 | 0.75 | KDM4E (0.37) | ADRA2AADRA2BADRA2CHPGDTSHR | |
| SCHEMBL84111 | 0.73 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520574-B1 | Thioxanthone derivatives | LAMBSON FINE CHEMICALS LIMITED (GB) | 2000-08-16 | — | — | EP | disclosed |
| US-5414092-A | Photoinitiators | INTERNATIONAL BIO-SYNTHETICS LIMITED (GB) | 1995-05-09 | — | — | US | disclosed |
| EP-0520574-A1 | Thioxanthone derivatives | GREAT LAKES FINE CHEMICALS LIMITED (GB) | 1992-12-30 | — | — | EP | disclosed |