Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5664674 | 0.79 | L3MBTL1 (0.39) | LMNASMN1; SMN2KDM4ETSHR | |
| SCHEMBL7007538 | 0.78 | NPSR1 (0.37) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL7702905 | 0.76 | KIF11 (0.38) | KIF11S1PR1NPC1RAB9ALMNA | |
| SCHEMBL9869167 | 0.75 | PTGS2 (0.51) | — | |
| SCHEMBL2406494 | 0.75 | KMT2A (0.42) | KIF11S1PR1NPC1RAB9ALMNA | |
| SCHEMBL19797926 | 0.73 | ESR2 (0.59) | KIF11S1PR1PTPN5GRIA4GRIA2 | |
| SCHEMBL8529551 | 0.72 | KIF11 (0.38) | KIF11S1PR1NPC1RAB9ALMNA | |
| SCHEMBL6397214 | 0.72 | KIF11 (0.35) | KIF11S1PR1NPC1RAB9ALMNA | |
| SCHEMBL16953849 | 0.72 | CA2 (0.35) | KIF11TSHR | |
| SCHEMBL6192365 | 0.70 | KDM4E (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6036766-A | SPINNING SOLUTIONS, PAINTS, COATINGS, PRINTING INKS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-03-14 | — | — | US | disclosed |