Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 4/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.46 |
| ▸ | KIFC1 | Q9BW19 | 5/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074686 | 0.91 | PSEN1 (0.42) | SLC1A3SLC1A2SLC1A1KIFC1KIF11 | |
| SCHEMBL8065580 | 0.85 | AKR1C3 (0.45) | AKR1C3AKR1C2 | |
| SCHEMBL8075087 | 0.85 | DCLRE1B (0.51) | MMP2MMP3GPR34MME | |
| SCHEMBL8073879 | 0.85 | DCLRE1B (0.51) | MMP2MMP3GPR34MME | |
| SCHEMBL8080154 | 0.82 | PPARG (0.41) | AKR1C3AKR1C2MME | |
| SCHEMBL8064541 | 0.82 | DCLRE1B (0.39) | SLC1A3SLC1A2SLC1A1MMP2MMP3 | |
| SCHEMBL8075538 | 0.82 | DCLRE1B (0.39) | SLC1A3SLC1A2SLC1A1MMP2MMP3 | |
| SCHEMBL8078431 | 0.81 | TTR (0.38) | SLC1A3SLC1A2SLC1A1AKR1C3AKR1C2 | |
| SCHEMBL8073803 | 0.81 | SLC1A3 (0.39) | SLC1A3SLC1A2SLC1A1AKR1C3AKR1C2 | |
| SCHEMBL8078295 | 0.81 | SLC1A3 (0.39) | SLC1A3SLC1A2SLC1A1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |