Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078804 | 0.91 | SLC1A3 (0.46) | MMP2MMP3KIFC1SLC1A3SLC1A2 | |
| SCHEMBL8065580 | 0.87 | AKR1C3 (0.45) | PPARDPPARAFFAR1AKR1C3AKR1C2 | |
| SCHEMBL8064541 | 0.86 | DCLRE1B (0.39) | ACEMMP1MMP2MMP3MMP7 | |
| SCHEMBL8075538 | 0.86 | DCLRE1B (0.39) | ACEMMP1MMP2MMP3MMP7 | |
| SCHEMBL8073803 | 0.83 | SLC1A3 (0.39) | ACESLC1A3SLC1A2SLC1A1AKR1C3 | |
| SCHEMBL8075742 | 0.83 | DCLRE1B (0.40) | ACEMMP1MMP2MMP3MMP7 | |
| SCHEMBL8078295 | 0.83 | SLC1A3 (0.39) | ACESLC1A3SLC1A2SLC1A1AKR1C3 | |
| SCHEMBL8075087 | 0.82 | DCLRE1B (0.51) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8073879 | 0.82 | DCLRE1B (0.51) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8080154 | 0.82 | PPARG (0.41) | PPARAFFAR1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |