Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl 4-Chlorophenylcarbamate SCHEMBL6258165 | 0.93 | ALDH1A1 (0.70) | ALDH1A1GAAHTTSMN1; SMN2RAB9A | |
| SCHEMBL5406539 | 0.90 | SMN1; SMN2 (0.64) | ALDH1A1GAAHTTSMN1; SMN2RAB9A | |
| Phenyl Phenylcarbamate SCHEMBL272994 | 0.87 | ALDH1A1 (0.76) | ALDH1A1GAAHTTSMN1; SMN2RAB9A | |
| SCHEMBL5416952 | 0.84 | ALDH1A1 (0.59) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL29881729 | 0.84 | ENPP3 (0.60) | ALDH1A1GAAHTTSMN1; SMN2RAB9A | |
| SCHEMBL9268642 | 0.84 | ALDH1A1 (0.72) | ALDH1A1GAAHTTSMN1; SMN2RAB9A | |
| SCHEMBL9480270 | 0.84 | ALDH1A1 (0.72) | ALDH1A1GAAHTTSMN1; SMN2RAB9A | |
| SCHEMBL5400971 | 0.83 | ALDH1A1 (0.57) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL3786216 | 0.83 | SMN1; SMN2 (0.71) | ALDH1A1GAAHTTSMN1; SMN2RAB9A | |
| SCHEMBL10192035 | 0.83 | KMT2A (0.55) | ALDH1A1GAAHTTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140210-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-04 | — | — | US | disclosed |
| EP-3781558-B1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2023-03-01 | — | — | EP | disclosed |
| US-20210363113-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-11-25 | — | — | US | disclosed |
| EP-3781558-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | The Regents Of The University Of Michigan (US) | 2021-02-24 | — | — | EP | disclosed |
| CN-107417578-B | N- (3, 5-dimethyl adamantane-1-yl) -N' -substituted phenylurea compound and preparation method and application thereof | 沈阳海诺威医药科技有限公司 | 2020-02-07 | — | — | CN | disclosed |
| WO-2019204447-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-10-24 | — | — | WO | disclosed |
| US-6143917-A | FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD | UBE INDUSTRIES, LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902014-A1 | PROCESS FOR PRODUCING ARYL CARBAMATES | UBE INDUSTRIES LIMITED (JP) | 1999-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363113-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | TFPI, F2, TFPI2 | ALDH1A1 571/4885GAA 1450/4885HTT 3629/4885 |
| US-20230140210-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | TFPI, F2, TFPI2 | ALDH1A1 571/4885GAA 1450/4885HTT 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.