Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665299 | 0.80 | LMNA (0.48) | ALDH1A1KMT2ASMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL7665506 | 0.78 | KDM4E (0.49) | ALDH1A1KMT2ASMN1; SMN2MEN1CHRNB2 | |
| SCHEMBL8401947 | 0.72 | CHRNB2 (0.47) | ALDH1A1KMT2ASMN1; SMN2MEN1CHRNB2 | |
| SCHEMBL7670029 | 0.69 | KMT2A (0.48) | ALDH1A1KMT2ASMN1; SMN2MEN1KCNA5 | |
| SCHEMBL7668225 | 0.69 | CHRNB2 (0.43) | ALDH1A1KMT2ASMN1; SMN2MEN1CHRNB2 | |
| SCHEMBL2186007 | 0.67 | CHRNB2 (0.54) | ALDH1A1KMT2ASMN1; SMN2MEN1CHRNB2 | |
| SCHEMBL7671836 | 0.67 | SMN1; SMN2 (0.43) | ALDH1A1KMT2ASMN1; SMN2MEN1KCNA5 | |
| SCHEMBL7669029 | 0.67 | CHRNB2 (0.46) | ALDH1A1KMT2ASMN1; SMN2MEN1KCNA5 | |
| SCHEMBL8066397 | 0.66 | KMT2A (0.47) | ALDH1A1KMT2AMEN1KCNA5CHRNB2 | |
| SCHEMBL7669280 | 0.66 | CHRNB2 (0.40) | ALDH1A1SMN1; SMN2CHRNB2CHRNA4NR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124297-A | COMBATTING INSECTS OR MITES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-26 | — | — | US | disclosed |