Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065479 | 0.82 | SMN1; SMN2 (0.48) | CHRNB2CHRNA4LMNARIPK1TRPM8 | |
| SCHEMBL7665506 | 0.77 | KDM4E (0.49) | CHRNB2CHRNA4KMT2AMEN1ALDH1A1 | |
| SCHEMBL7668225 | 0.75 | CHRNB2 (0.43) | CHRNB2CHRNA4LMNATRPM8KMT2A | |
| SCHEMBL2186007 | 0.73 | CHRNB2 (0.54) | CHRNB2CHRNA4LMNARIPK1TRPM8 | |
| SCHEMBL8066296 | 0.72 | ALDH1A1 (0.39) | CHRNB2CHRNA4LMNAKMT2AMEN1 | |
| SCHEMBL2187051 | 0.71 | KDM4E (0.61) | CHRNB2CHRNA4LMNARIPK1TRPM8 | |
| SCHEMBL8066367 | 0.69 | RIPK1 (0.53) | CHRNB2CHRNA4LMNARIPK1KMT2A | |
| SCHEMBL12277668 | 0.69 | RIPK1 (0.59) | CHRNB2CHRNA4LMNARIPK1KMT2A | |
| SCHEMBL28710701 | 0.68 | NAPRT (0.54) | KMT2AMEN1SMN1; SMN2PKMGAA | |
| SCHEMBL29438510 | 0.68 | NAPRT (0.54) | KMT2AMEN1SMN1; SMN2PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5175301-A | Insecticide, miticide, pesticide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |