Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201904 | 0.88 | MEN1 (0.74) | ALDH1A1CYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL343011 | 0.83 | MAPT (0.77) | ALDH1A1CYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL10426457 | 0.81 | ALDH1A1 (0.59) | ALDH1A1CYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL2456224 | 0.81 | ALDH1A1 (0.64) | ALDH1A1CYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL14662953 | 0.81 | MAPT (0.69) | ALDH1A1CYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL28538184 | 0.80 | MMP8 (0.50) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL27551411 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL2283965 | 0.78 | ALDH1A1 (0.64) | ALDH1A1CYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL28219066 | 0.78 | ALDH1A1 (0.73) | ALDH1A1CYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL3413576 | 0.78 | ALDH1A1 (0.73) | ALDH1A1CYP3A4KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090184-C | Heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-04 | — | — | CN | disclosed |
| EP-0736018-B1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-6025375-A | INHIBITORY ACTIVITY ON PLATELET AGGREGATION, VASODILATING ACTIVITY, ANTIHYPERTENSIVE ACTIVITY OR THE LIKE AND ARE PROSTAGLANDIN I.SUB.2 AGONISTS, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| CN-1046714-C | Diaryl oxazole derivative and its preparation method, application and pharmaceutical composition | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-11-24 | — | — | CN | disclosed |
| CN-1229795-A | Heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-09-29 | — | — | CN | disclosed |
| CN-1138328-A | Heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| WO-1995017393-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-29 | — | — | WO | disclosed |