Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19051467 | 0.88 | GNPAT (0.36) | KMT2ACA1CA2DRD1HDAC1 | |
| SCHEMBL18381413 | 0.85 | HDAC1 (0.40) | KMT2ACA1CA2HDAC1MEN1 | |
| SCHEMBL7644948 | 0.82 | MMP3 (0.43) | CTSSCTSK | |
| SCHEMBL7644955 | 0.82 | MMP3 (0.43) | CTSSCTSK | |
| SCHEMBL30399454 | 0.81 | GAA (0.45) | KMT2ACA1CA2HTTATM | |
| SCHEMBL19059660 | 0.81 | SIRT6 (0.34) | KMT2ACA1CA2SIRT6SIRT1 | |
| SCHEMBL514228 | 0.80 | QPCT (0.49) | KMT2AQPCTQPCTLHTTCYP1A2 | |
| SCHEMBL12329054 | 0.80 | HTT (0.37) | KMT2ACA1CA2HTTATM | |
| SCHEMBL2608923 | 0.79 | RECQL (0.43) | KMT2AHTTATMCYP1A2CYP3A4 | |
| SCHEMBL18676335 | 0.79 | CTSS (0.39) | KMT2ACA1CA2HDAC1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726895-B1 | PSEUDODIPEPTIDE PRODUCT HAVING AN IMIDAZOLE GROUPING AND APPLICATIONS | EXSYMOL SA (MC) | 2000-07-05 | — | — | EP | claimed |
| EP-0726895-B1 | PSEUDODIPEPTIDE PRODUCT HAVING AN IMIDAZOLE GROUPING AND APPLICATIONS | EXSYMOL SA (MC) | 2000-07-05 | — | — | EP | disclosed |
| US-6046340-A | COUPLING N-PROTECTED AND O-ACTIVATED ALPHA AMINO ACID WITH HISTAMINE OR METHYL-SUBSTITUTED HISTAMINE; FOR USE IN THERAPEUTIC, COSMETIC AND FOOD FIELDS | EXSYMOL SOCIETE ANONYME MONEGASQUE (MC) | 2000-04-04 | — | — | US | disclosed |
| EP-0726895-A1 | PSEUDODIPEPTIDE PRODUCT HAVING AN IMIDAZOLE GROUPING AND APPLICATIONS | EXSYMOL S.A.M. (MC) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012581-A1 | PSEUDODIPEPTIDE PRODUCT HAVING AN IMIDAZOLE GROUPING AND APPLICATIONS | EXSYMOL SOCIETE ANONYME MONEGASQUE (MC) | 1995-05-11 | — | — | WO | disclosed |