Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | RXRB | P28702 | 3/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066704 | 1.00 | GID4 (0.43) | GID4KDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL9006849 | 0.88 | NR4A2 (0.42) | KDM4EHTTTDP1SMN1; SMN2LMNA | |
| SCHEMBL9006842 | 0.87 | NR4A2 (0.41) | KDM4EHTTTDP1SMN1; SMN2LMNA | |
| SCHEMBL8065993 | 0.86 | FABP4 (0.50) | KDM4EHPGDPTGIRMEN1KMT2A | |
| SCHEMBL8065990 | 0.86 | FABP4 (0.50) | KDM4EHPGDPTGIRMEN1KMT2A | |
| SCHEMBL8055531 | 0.82 | PTGIR (0.47) | KDM4EHTTTDP1SMN1; SMN2LMNA | |
| SCHEMBL8055530 | 0.82 | PTGIR (0.47) | KDM4EHTTTDP1SMN1; SMN2LMNA | |
| SCHEMBL9006916 | 0.73 | RXRA (0.41) | KDM4ELMNARXRARXRBNR4A2 | |
| SCHEMBL8065136 | 0.73 | KDM4E (0.44) | GID4KDM4EHTTTDP1SMN1; SMN2 | |
| SCHEMBL8074838 | 0.72 | KDM4E (0.46) | KDM4EHTTTDP1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736018-B1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-6025375-A | INHIBITORY ACTIVITY ON PLATELET AGGREGATION, VASODILATING ACTIVITY, ANTIHYPERTENSIVE ACTIVITY OR THE LIKE AND ARE PROSTAGLANDIN I.SUB.2 AGONISTS, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| WO-1995017393-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-29 | — | — | WO | disclosed |