SCHEMBL2777971

SCHEMBL2777971

CCc1ccc(Nc2ccc(N)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.54
ALDH1A1 P00352 3/20 0.54
MAPT P10636 3/20 0.54
CYP1A2 P05177 2/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
ALOX12 P18054 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
HTT P42858 1/20 0.54
NR4A1 P22736 1/20 0.52
IL6 P05231 1/20 0.51
STAT3 P40763 1/20 0.51
RAD52 P43351 1/20 0.50
TAAR1 Q96RJ0 1/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
EGFR P00533 1/20 0.45
GFER P55789 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49571 0.88 RAB9A (0.55) CYP3A4ALDH1A1MAPTCYP1A2CYP2C9
SCHEMBL4409 0.85
Ethane SCHEMBL7209292 0.83 TAAR1 (0.59) CYP3A4ALDH1A1MAPTL3MBTL1TAAR1
Ammonia Solution, Strong SCHEMBL11510939 0.83 TAAR1 (0.59) CYP3A4ALDH1A1MAPTL3MBTL1TAAR1
Hydrochloric Acid SCHEMBL2866143 0.83 TAAR1 (0.59) CYP3A4ALDH1A1MAPTL3MBTL1TAAR1
Bromide SCHEMBL29228010 0.83 TAAR1 (0.59) CYP3A4ALDH1A1MAPTL3MBTL1TAAR1
SCHEMBL27350060 0.83 GFER (0.52) CYP3A4ALDH1A1MAPTCYP1A2CYP2C9
SCHEMBL15977 0.81 CYP3A4 (0.70) CYP3A4ALDH1A1MAPTCYP1A2CYP2C9
SCHEMBL13769425 0.81 UCHL1 (0.55) CYP3A4ALDH1A1MAPTCYP1A2CYP2C9
SCHEMBL31285785 0.81 CYP3A4 (0.70) CYP3A4ALDH1A1MAPTCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4154614-A ACRYLONITRILE-HYDROLYSED POLYVINYL ACETATE GRAFT POLYMER NIPPON PAINT CO., LTD. (JP) 1979-05-15 US claimed
EP-2952505-B1 A HINDERED PHENOL COMPOUND, PREPARATION THEREOF AND USE THEREOF AS AN ANTIOXIDANT CHINA PETROLEUM & CHEM CORP (CN) 2018-05-23 EP disclosed
US-9512380-B2 Hindered phenol compound, preparation thereof and use thereof as an antioxidant CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-12-06 US disclosed
US-20150353858-A1 HINDERED PHENOL COMPOUND, PREPARATION THEREOF AND USE THEREOF AS AN ANTIOXIDANT RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC (CN) 2015-12-10 US disclosed
EP-2952505-A1 A hindered phenol compound, preparation thereof and use thereof as an antioxidant China Petroleum & Chemical Corporation (CN) 2015-12-09 EP disclosed
US-7767381-B2 Photosensitive resin composition, and photosensitive film and stencil for screen printing using the photosensitive composition MURAKAMI CO., LTD. (JP) 2010-08-03 US disclosed
US-20090099275-A1 Photosensitive Resin Composition, and Photosensitive Film and Stencil for Screen Printing Using the Photosensitive Composition MURAKAMI CO., LTD. (JP) 2009-04-16 US disclosed
EP-2019128-A1 PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCED THEREFROM, PHOTOSENSITIVE FILM AND STENCIL FOR SCREEN PRINTING Murakami Co., Ltd. (JP) 2009-01-28 EP disclosed
US-6503683-B1 Polyvinylpyridine (or pyridinium) containing films that can be cast from aqueous solutions which, after imaging and in contact with an alkaline liquid such as a screen printing ink forms water resistant screen stencils THE CHROMALINE CORPORATION 2003-01-07 US disclosed
US-6248498-B1 PHOTOSENSITIVE MODIFIED VINYL ALCOHOL POLYMER GRAFTED WITH FURANYL QUATERNARY HETEROCYCLE FOR HYDROPHOBIC POLYMER THE CHROMALINE CORPORATION 2001-06-19 US disclosed
US-5556735-A PATTERNED SOLDER RESIST ON A PRINTED CIRCUIT COATES BROTHERS PLC (GB) 1996-09-17 US disclosed
US-5506089-A CONTAINING HETEROCYCLIC QUATERNARY PENDANT GROUP THE CHROMALINE CORPORATION (US) 1996-04-09 US disclosed
WO-1995012148-A1 SCREEN PRINTING STENCIL COMPOSITION WITH IMPROVED WATER RESISTANCE THE CHROMALINE CORPORATION (US) 1995-05-04 WO disclosed
EP-0536272-A1 IMAGE-FORMING PROCESS COATES BROTHERS PLC (GB) 1993-04-14 EP disclosed
WO-1992000552-A1 IMAGE-FORMING PROCESS COATES BROTHERS PLC (GB) 1992-01-09 WO disclosed
EP-0130804-B1 PHOTOSENSITIVE RESIN COMPOSITION KOGYO GIJUTSUIN (JP) 1989-02-08 EP disclosed
US-4564580-A SAPONIFIED VINYL ACETATE POLYMER REACTED WITH STRYLPYRIDINIUM OR S KOGYO GIJUTSUIN (JP) 1986-01-14 US disclosed
EP-0130804-A2 Photosensitive resin composition KOGYO GIJUTSUIN (JP) 1985-01-09 EP disclosed
US-4304939-A Preparation of N-phenyl-N-alkylphenylenediamines UOP INC. (US) 1981-12-08 US disclosed
US-4154614-A ACRYLONITRILE-HYDROLYSED POLYVINYL ACETATE GRAFT POLYMER NIPPON PAINT CO., LTD. (JP) 1979-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150353858-A1 HINDERED PHENOL COMPOUND, PREPARATION THEREOF AND USE THEREOF AS AN ANTIOXIDANT GPX4, CAT, GPX1 CYP3A4 944/4885ALDH1A1 194/4885MAPT 1938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.