Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26088637 | 0.95 | MAPT (0.50) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27903338 | 0.88 | HTR6 (0.53) | MAPTALDH1A1MEN1KMT2ALOXL2 | |
| SCHEMBL27747311 | 0.87 | KDM4E (0.62) | MAPTALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL27473567 | 0.86 | ALDH1A1 (0.60) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28406911 | 0.84 | LOXL2 (0.71) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8067239 | 0.84 | RAPGEF4 (0.54) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27977809 | 0.84 | ENPP2 (0.55) | MAPTALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL20049388 | 0.82 | MAPT (0.73) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 | |
| Biphenyl SCHEMBL27570267 | 0.81 | TAAR1 (0.55) | MAPTALDH1A1CYP3A4ALOX12L3MBTL1 | |
| SCHEMBL27623210 | 0.79 | ALDH1A1 (0.61) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208406-A | Synthesis of phenyl-substituted polyfluoroanthenes and the use thereof | BASF AG (DE) | 2008-06-25 | — | — | CN | disclosed |