Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | OXTR | P30559 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806780 | 0.83 | SMN1; SMN2 (1.00) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL10053396 | 0.77 | SMN1; SMN2 (0.86) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL806438 | 0.75 | SMN1; SMN2 (0.83) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL4259973 | 0.73 | PKM (0.67) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL806760 | 0.70 | SMN1; SMN2 (0.75) | SMN1; SMN2HPGDATML3MBTL1LMNA | |
| SCHEMBL5100118 | 0.69 | MAPT (0.60) | SMN1; SMN2HPGDL3MBTL1LMNAGAA | |
| SCHEMBL2760607 | 0.69 | SMN1; SMN2 (0.60) | SMN1; SMN2L3MBTL1LMNAGAAALDH1A1 | |
| SCHEMBL25984793 | 0.68 | HSD11B1 (0.81) | SMN1; SMN2HPGDLMNAGAAALDH1A1 | |
| SCHEMBL6206191 | 0.68 | ALDH1A1 (0.69) | SMN1; SMN2L3MBTL1LMNAGAAALDH1A1 | |
| SCHEMBL798762 | 0.68 | MAPT (0.67) | SMN1; SMN2HPGDATML3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616073-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | Microbiotix, Inc. (US) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037119-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | MICROBIOTIX, INC. (US) | 2012-03-22 | — | — | WO | disclosed |