Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28454360 | 0.84 | GAA (0.62) | GAANR1H4ALDH1A1TSHRNFKB1 | |
| SCHEMBL8066867 | 0.83 | PDE4B (0.46) | PDE4DALDH1A1TSHRLMNAHTT | |
| SCHEMBL15906176 | 0.83 | GAA (0.55) | GAANR1H4PDE4DALDH1A1TSHR | |
| SCHEMBL8014205 | 0.83 | PDE4B (0.46) | PDE4DALDH1A1TSHRLMNAHTT | |
| SCHEMBL8067030 | 0.83 | PDE4D (0.49) | PDE4DALDH1A1TSHRLMNAHTT | |
| SCHEMBL8065449 | 0.82 | PDE4D (0.63) | GAAPDE4DALDH1A1TSHRNFKB1 | |
| SCHEMBL8028169 | 0.82 | PDE4D (0.49) | PDE4DFFAR1PDE4BCTSA | |
| SCHEMBL21076208 | 0.79 | GAA (0.72) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL8066904 | 0.79 | PDE4D (0.54) | GAAPDE4DKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8071940 | 0.79 | PDE4D (0.51) | PDE4DFFAR1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067600-A2 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |