Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 15/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066788 | 0.92 | PADI4 (0.40) | PADI4IDO1TDO2NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL8057444 | 0.89 | IP6K1 (0.35) | PADI4 | |
| Trifluoroacetic Acid SCHEMBL8068251 | 0.85 | IP6K1 (0.39) | PADI4NPC1RAB9AMAPT | |
| Trifluoroacetic Acid SCHEMBL8069127 | 0.83 | TGFBR1 (0.38) | NPC1RAB9AKDM4EMAPTNFKB1 | |
| Trifluoroacetic Acid SCHEMBL8067343 | 0.81 | CYSLTR1 (0.39) | NPC1RAB9AKDM4EMAPT | |
| SCHEMBL8073308 | 0.79 | IP6K1 (0.41) | NPC1RAB9AMAPT | |
| SCHEMBL8073292 | 0.79 | IP6K1 (0.41) | NPC1RAB9AMAPT | |
| SCHEMBL8069058 | 0.76 | IP6K1 (0.46) | PADI4NPC1RAB9AKDM4EMAPT | |
| SCHEMBL8069062 | 0.76 | IP6K1 (0.46) | PADI4NPC1RAB9AKDM4EMAPT | |
| SCHEMBL8068015 | 0.76 | PADI4 (0.39) | PADI4IDO1TDO2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |