Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068049 | 1.00 | TRPA1 (0.51) | TRPA1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8066991 | 0.94 | NPC1 (0.43) | TRPA1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8066994 | 0.94 | NPC1 (0.43) | TRPA1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7838292 | 0.87 | ALOX15 (0.45) | MEN1KMT2AMAPTHPGDCYP3A4 | |
| SCHEMBL8058234 | 0.86 | THRB (0.41) | SMN1; SMN2MAPTHPGDALDH1A1TP53 | |
| SCHEMBL8058240 | 0.86 | THRB (0.41) | SMN1; SMN2MAPTHPGDALDH1A1TP53 | |
| SCHEMBL7828093 | 0.85 | PADI4 (0.39) | MEN1KMT2ASMN1; SMN2MAPTHPGD | |
| SCHEMBL7828091 | 0.85 | PADI4 (0.39) | MEN1KMT2ASMN1; SMN2MAPTHPGD | |
| SCHEMBL8067254 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL8067250 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2AMAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |