SCHEMBL8068326

SCHEMBL8068326

NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 6/20 0.61
▸ ACE P12821 6/20 0.56
▸ CPA1 P15085 4/20 0.56
▸ ACE2 Q9BYF1 4/20 0.56
▸ GNPAT O15228 1/20 0.55
▸ ITGB3 P05106 1/20 0.55
▸ ITGA2B P08514 1/20 0.55
▸ CTSC P53634 2/20 0.55
▸ LMNA P02545 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8068319 1.00 MME (0.61) MMEACECPA1ACE2GNPAT
SCHEMBL4432590 0.94 CTSC (0.60) MMEACEITGB3ITGA2BCTSC
SCHEMBL232698 0.94 CTSC (0.60) MMEACEITGB3ITGA2BCTSC
SCHEMBL232699 0.94 CTSC (0.60) MMEACEITGB3ITGA2BCTSC
SCHEMBL31607204 0.93 MME (0.55) MMEACECPA1ACE2GNPAT
SCHEMBL29350849 0.93 MME (0.63) MMEACE
SCHEMBL29603463 0.93 MME (0.63) MMEACE
SCHEMBL13588078 0.93 MME (0.63) MMEACE
SCHEMBL29602654 0.93 MME (0.63) MMEACE
SCHEMBL30900762 0.93 MME (0.59) MMEACECPA1ACE2GNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663205-A1 POLYMER-DRUG CONJUGATE, INTERMEDIATE THEREOF, AND USE THEREOF Shanghai Best-Link Bioscience, LLC (CN) 2025-12-17 — — EP claimed
US-20250255977-A1 EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) 2025-08-14 — — US claimed
US-12350337-B2 Polymeric drug delivery conjugates and methods of making and using thereof UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-07-08 — — US claimed
WO-2024222960-A1 POLYMER-DRUG CONJUGATE, INTERMEDIATE THEREOF, AND USE THEREOF 上海弼领生物技术有限公司 2024-10-31 — — WO claimed
EP-4431116-A1 EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF Shanghai Best-Link Bioscience, LLC (CN) 2024-09-18 — — EP claimed
CN-118284435-A Drug conjugate based on epsilon-poly-L-lysine, intermediate and application thereof 上海弼领生物技术有限公司 2024-07-02 — — CN claimed
US-11801307-B2 Antibody-polymer-drug conjugates UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2023-10-31 — — US claimed
WO-2023078464-A1 EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF 上海弼领生物技术有限公司 2023-05-11 — — WO claimed
EP-4045087-A1 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF University of Utah Research Foundation (US) 2022-08-24 — — EP claimed
US-20220249682-A1 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF UTAH RESEARCH FOUNDATION 2022-08-11 — — US claimed
EP-4746916-A2 CLEAVABLE POLYMER-DRUG CONJUGATES FOR ALZHEIMER'S DISEASE University of Utah Research Foundation (US) 2026-05-27 — — EP disclosed
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 — — US disclosed
EP-4663205-A1 POLYMER-DRUG CONJUGATE, INTERMEDIATE THEREOF, AND USE THEREOF Shanghai Best-Link Bioscience, LLC (CN) 2025-12-17 — — EP disclosed
US-20250255977-A1 EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) 2025-08-14 — — US disclosed
US-12350337-B2 Polymeric drug delivery conjugates and methods of making and using thereof UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-07-08 — — US disclosed
EP-0425104-A1 Column packing material SHISEIDO COMPANY LIMITED (JP) 1991-05-02 — — EP disclosed
US-4941974-A Method of making liquid chromatography dual zone packing materials DOW CORNING CORPORATION (US) 1990-07-17 — — US disclosed
US-4855054-A BIOLOGICAL ANALYSIS USING A POROUS SUPPORT WITH PERFLUORO-ALKYLSILYL GROUPS AS EXTERNAL LIPOPHOBIC PHASE TO REJECT PROTEINS; INTERNAL LIPOPHILIC PHASE ABSORBS DRUGS AND SMALL MOLECULES DOW CORNING CORPORATION (US) 1989-08-08 — — US disclosed
EP-0295809-A2 Liquid chromatography dual zone packing materials and method for making and using same DOW CORNING CORPORATION (US) 1988-12-21 — — EP disclosed
US-4778600-A LIPOPHOBIC FLUOROCARBON PHASE REJECTS PROTEINS; LIPOPHILIC PARTITIONING PHASE RETAINS SMALL MOLECULES; BLOOD ANALYSIS DOW CORNING CORPORATION (US) 1988-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP MME 824/4885ACE 1190/4885CPA1 245/4885
US-12350337-B2 Polymeric drug delivery conjugates and methods of making and using thereof PDCD1LG2, CD274, PDCD1 MME 1034/4885ACE 1554/4885CPA1 1598/4885
US-11801307-B2 Antibody-polymer-drug conjugates FCGR1A, FCGR2A, CD79B MME 880/4885ACE 2799/4885CPA1 2356/4885
US-20220249682-A1 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF PDCD1LG2, CD274, PDCD1 MME 1034/4885ACE 1554/4885CPA1 1598/4885
US-20250255977-A1 EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF SLC7A1, KARS1, LNPEP MME 946/4885ACE 1805/4885CPA1 1800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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