Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063405 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDSMN1; SMN2CCR6 | |
| SCHEMBL8063402 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDSMN1; SMN2CCR6 | |
| SCHEMBL8065764 | 0.76 | AKT1 (0.38) | ALDH1A1MAPTHPGDSMN1; SMN2CCR6 | |
| SCHEMBL8065760 | 0.76 | AKT1 (0.38) | ALDH1A1MAPTHPGDSMN1; SMN2CCR6 | |
| SCHEMBL8063733 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDSMN1; SMN2CCR6 | |
| SCHEMBL8063731 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDSMN1; SMN2CCR6 | |
| SCHEMBL3228005 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDCCR6PAX8 | |
| SCHEMBL1484730 | 0.74 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TSHRCA12CA1 | |
| SCHEMBL27445566 | 0.73 | SMN1; SMN2 (0.48) | ALDH1A1MAPTHPGDSMN1; SMN2TSHR | |
| SCHEMBL3254015 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDCCR6PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162925-A | Antibiotic for methicillin resistant bacteria | RESEARCH CORPORATION TECH., INC. (US) | 2000-12-19 | — | — | US | disclosed |
| US-6110925-A | EFFECTIVE AGAINST STAPHYLOCOCCUS; ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-08-29 | — | — | US | disclosed |