Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063731 | 1.00 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL8063402 | 0.91 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MAPK1TDP1CCR6 | |
| SCHEMBL8063405 | 0.91 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MAPK1TDP1CCR6 | |
| SCHEMBL8065760 | 0.84 | AKT1 (0.38) | ALDH1A1L3MBTL1CCR6PAX8MAPT | |
| SCHEMBL8065764 | 0.84 | AKT1 (0.38) | ALDH1A1L3MBTL1CCR6PAX8MAPT | |
| SCHEMBL8063735 | 0.76 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL8068382 | 0.75 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL8058467 | 0.73 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL8047952 | 0.72 | KDM4E (0.48) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL8047957 | 0.72 | KDM4E (0.48) | ALDH1A1L3MBTL1TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162925-A | Antibiotic for methicillin resistant bacteria | RESEARCH CORPORATION TECH., INC. (US) | 2000-12-19 | — | — | US | disclosed |
| US-6110925-A | EFFECTIVE AGAINST STAPHYLOCOCCUS; ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-08-29 | — | — | US | disclosed |
| EP-1003727-A1 | ANTIBIOTIC FOR METHICILLIN RESISTANT BACTERIA | RESEARCH CORPORATION TECHNOLOGIES (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007685-A1 | ANTIBIOTIC FOR METHICILLIN RESISTANT BACTERIA | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1999-02-18 | — | — | WO | disclosed |