Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065764 | 1.00 | AKT1 (0.38) | AKT1SMN1; SMN2ALDH1A1SYKLTA4H | |
| SCHEMBL8063405 | 0.90 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1L3MBTL1POLBMAPT | |
| SCHEMBL8063402 | 0.90 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1L3MBTL1POLBMAPT | |
| SCHEMBL8063733 | 0.84 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL8063731 | 0.84 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL7342215 | 0.79 | SYK (0.46) | AKT1SMN1; SMN2ALDH1A1SYKLMNA | |
| SCHEMBL7342211 | 0.79 | SYK (0.46) | AKT1SMN1; SMN2ALDH1A1SYKLMNA | |
| SCHEMBL8068382 | 0.76 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL31384541 | 0.76 | RAB9A (0.46) | AKT1SMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8065769 | 0.75 | SYK (0.43) | AKT1SMN1; SMN2ALDH1A1SYKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162925-A | Antibiotic for methicillin resistant bacteria | RESEARCH CORPORATION TECH., INC. (US) | 2000-12-19 | — | — | US | disclosed |
| US-6110925-A | EFFECTIVE AGAINST STAPHYLOCOCCUS; ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-08-29 | — | — | US | disclosed |