Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068785 | 0.89 | ALDH1A1 (0.40) | LMNAALDH1A1HTTSMN1; SMN2SCN9A | |
| SCHEMBL8059376 | 0.89 | SCN9A (0.44) | LMNAALDH1A1HTTSMN1; SMN2SCN9A | |
| SCHEMBL8059561 | 0.87 | MRGPRX1 (0.41) | SCN9A | |
| Hydrochloric Acid SCHEMBL8073473 | 0.83 | THRA (0.36) | — | |
| SCHEMBL8059368 | 0.78 | SCN9A (0.38) | SCN9A | |
| SCHEMBL8070496 | 0.76 | MRGPRX1 (0.43) | — | |
| SCHEMBL8070524 | 0.76 | FLT1 (0.42) | SCN9A | |
| Rimeporide SCHEMBL1019630 | 0.75 | SLC9A1 (0.55) | — | |
| Rimeporide SCHEMBL29404681 | 0.75 | SLC9A1 (0.55) | — | |
| Rimeporide SCHEMBL1021018 | 0.74 | SLC9A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |