Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | TARS1 | P26639 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 3/20 | 0.32 |
| ▸ | FLT4 | P35916 | 3/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068785 | 0.89 | ALDH1A1 (0.40) | SCN9A | |
| SCHEMBL8059561 | 0.87 | MRGPRX1 (0.41) | SCN9AMRGPRX1MCL1BCL2L1TARS1 | |
| SCHEMBL8070524 | 0.86 | FLT1 (0.42) | SCN9AMCL1BCL2L1FLT1FLT4 | |
| SCHEMBL8070496 | 0.79 | MRGPRX1 (0.43) | MRGPRX1TARS1 | |
| SCHEMBL8068547 | 0.78 | LMNA (0.41) | SCN9A | |
| SCHEMBL8059376 | 0.78 | SCN9A (0.44) | SCN9A | |
| SCHEMBL8073839 | 0.72 | MRGPRX1 (0.40) | SCN9AMRGPRX1FLT1FLT4KDR | |
| Hydrochloric Acid SCHEMBL8073473 | 0.72 | THRA (0.36) | — | |
| SCHEMBL8068459 | 0.72 | SCN9A (0.36) | SCN9A | |
| SCHEMBL8446348 | 0.70 | CA2 (0.43) | MRGPRX1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |