Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HLCS | P50747 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716129 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AHLCSLMNA | |
| SCHEMBL6360842 | 0.76 | LMNA (0.47) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL9186739 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ALMNAITGB3 | |
| SCHEMBL11492447 | 0.73 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AHLCSLMNA | |
| SCHEMBL11491775 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHLCSLMNA | |
| SCHEMBL11483368 | 0.71 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AHLCSLMNA | |
| SCHEMBL11492446 | 0.70 | ADH1B (0.36) | ALDH1A1MEN1KMT2AHLCSLMNA | |
| SCHEMBL11495094 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AHLCSLMNA | |
| SCHEMBL11486565 | 0.70 | GAA (0.34) | ALDH1A1MEN1KMT2AHLCSLMNA | |
| SCHEMBL11492479 | 0.70 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ALMNAITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018053-A | Process for the preparation of chiral, nonracemic (4-aryl-2,5-dioxoimidazolidin-1-yl) acetic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |