Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.62 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12489466 | 0.92 | PAX8 (0.56) | SIGMAR1HRH2DRD4PAX8ALDH1A1 | |
| SCHEMBL12488080 | 0.92 | PAX8 (0.56) | SIGMAR1HRH2DRD4PAX8ALDH1A1 | |
| SCHEMBL12488076 | 0.92 | PAX8 (0.56) | SIGMAR1HRH2DRD4PAX8ALDH1A1 | |
| SCHEMBL12488083 | 0.92 | PAX8 (0.56) | SIGMAR1HRH2DRD4PAX8ALDH1A1 | |
| SCHEMBL19559108 | 0.82 | SIGMAR1 (0.51) | SIGMAR1HRH2MEN1KMT2ADRD4 | |
| SCHEMBL7072989 | 0.82 | FUCA1 (0.55) | SIGMAR1ALDH1A1 | |
| SCHEMBL4877680 | 0.82 | FAAH (0.53) | SIGMAR1KMT2APAX8FAAHALDH1A1 | |
| SCHEMBL13602414 | 0.80 | SIGMAR1 (0.47) | SIGMAR1HRH2MEN1KMT2ADRD2 | |
| SCHEMBL6572711 | 0.80 | SIGMAR1 (0.64) | SIGMAR1HRH2MEN1KMT2ADRD4 | |
| SCHEMBL14197151 | 0.80 | LMNA (0.54) | SIGMAR1KMT2AFAAHALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096755-A | N-substituted azabicycloalkane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-01 | — | — | US | disclosed |
| EP-0731802-A1 | N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES AS NEUROLEPTIKA ASF | BASF AKTIENGESELLSCHAFT (DE) | 1996-09-18 | — | — | EP | disclosed |
| WO-1996026978-A1 | IMPROVED SELF-LUBRICATING THERMOPLASTIC POLYMER COMPOSITION | HOECHST CELANESE CORPORATION (US) | 1996-09-06 | — | — | WO | disclosed |
| EP-0728136-A1 | N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES, THEIR PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995015327-A1 | N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES AS NEUROLEPTIKA ASF | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-08 | — | — | WO | disclosed |
| WO-1995013279-A1 | N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES, THEIR PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-18 | — | — | WO | disclosed |