Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 13/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388287 | 0.91 | CNR1 (0.45) | — | |
| SCHEMBL8068011 | 0.90 | MAPT (0.43) | EPORALOX5 | |
| SCHEMBL8069613 | 0.90 | PLAAT3 (0.38) | EPOR | |
| SCHEMBL8058871 | 0.89 | ALDH1A1 (0.42) | ALOX5 | |
| SCHEMBL1718512 | 0.89 | NPY1R (0.42) | — | |
| SCHEMBL8059066 | 0.86 | CNR1 (0.47) | — | |
| SCHEMBL8069325 | 0.86 | CNR1 (0.39) | — | |
| SCHEMBL8069355 | 0.86 | CNR1 (0.47) | — | |
| SCHEMBL8073040 | 0.85 | NPY1R (0.41) | — | |
| SCHEMBL9194825 | 0.84 | ALDH1A1 (0.42) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |