Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638353 | 0.81 | RAB9A (0.54) | RAB9AKMT2ANPC1MEN1POLB | |
| SCHEMBL8074716 | 0.80 | MAPT (0.57) | KMT2AMEN1POLBMAPTCYP3A4 | |
| SCHEMBL6064547 | 0.77 | KMT2A (0.47) | RAB9AKMT2ANPC1MEN1MAPT | |
| SCHEMBL27889259 | 0.77 | POLB (0.50) | RAB9AKMT2ANPC1MEN1NR1H4 | |
| SCHEMBL159113 | 0.77 | ALDH1A1 (0.56) | RAB9AKMT2ANPC1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL27586436 | 0.75 | ALDH1A1 (0.54) | RAB9AKMT2ANPC1MEN1MAPT | |
| SCHEMBL10814976 | 0.73 | NR1H4 (0.62) | RAB9AKMT2ANPC1MEN1NR1H4 | |
| SCHEMBL21295402 | 0.72 | SAE1 (0.58) | RAB9AKMT2ANPC1MEN1MAPT | |
| SCHEMBL30744047 | 0.72 | SAE1 (0.58) | RAB9AKMT2ANPC1MEN1MAPT | |
| SCHEMBL10179565 | 0.71 | KMT2A (0.51) | RAB9AKMT2ANPC1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017685-A1 | NEW 2-(3H)-OXAZOLONE DERIVATIVES | ALMIRALL-PRODESFARMA, S.A. (ES) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999014205-A1 | NEW 2-(3H)-OXAZOLONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 1999-03-25 | — | — | WO | disclosed |