Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TAS2R14 | Q9NYV8 | 14/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059120 | 0.85 | MAPT (0.64) | MAPTTAS2R14MEN1KMT2ACNR2 | |
| SCHEMBL8059124 | 0.81 | TAS2R14 (0.59) | MAPTTAS2R14MEN1KMT2APOLB | |
| SCHEMBL8069690 | 0.80 | RAB9A (0.58) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL8059144 | 0.80 | TAS2R14 (0.57) | MAPTTAS2R14MEN1KMT2APOLB | |
| SCHEMBL8074805 | 0.75 | MAPT (0.53) | MAPTTAS2R14MEN1KMT2APOLB | |
| SCHEMBL8070251 | 0.75 | MAPT (0.56) | MAPTTAS2R14MEN1KMT2APOLB | |
| SCHEMBL6300788 | 0.74 | TAS2R14 (0.77) | MAPTTAS2R14MEN1KMT2APOLB | |
| SCHEMBL8074725 | 0.73 | MAPT (0.63) | MAPTTAS2R14MEN1KMT2ACNR2 | |
| SCHEMBL8073250 | 0.73 | TAS2R14 (0.61) | MAPTTAS2R14MEN1KMT2APOLB | |
| SCHEMBL8069963 | 0.72 | TAS2R14 (0.64) | MAPTTAS2R14MEN1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017685-A1 | NEW 2-(3H)-OXAZOLONE DERIVATIVES | ALMIRALL-PRODESFARMA, S.A. (ES) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999014205-A1 | NEW 2-(3H)-OXAZOLONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 1999-03-25 | — | — | WO | disclosed |