Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638353 | 0.82 | RAB9A (0.54) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL3690329 | 0.82 | RAB9A (0.54) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL159113 | 0.81 | ALDH1A1 (0.56) | KMT2AMEN1RAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL27586436 | 0.79 | ALDH1A1 (0.54) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL7196858 | 0.78 | MAPT (0.61) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL8069690 | 0.77 | RAB9A (0.58) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL1555065 | 0.76 | KMT2A (0.54) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL3468116 | 0.76 | ALDH1A1 (0.47) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL8069542 | 0.76 | ALDH1A1 (0.47) | KMT2AMEN1MAPTKDM4ECES1 | |
| SCHEMBL31674346 | 0.76 | NPSR1 (0.56) | KMT2AMEN1MAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019166-B2 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2006-03-28 | — | — | US | disclosed |
| US-20050182274-A1 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2005-08-18 | — | — | US | disclosed |
| US-6867310-B1 | Arylation and vinylation of activated carbons | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182274-A1 | Method for the production of 2,4,5-trimethylphenyl acetic acid | CA6, DDC, HACL2 | KMT2A 184/4885MEN1 523/4885RAB9A 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.