Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14558326 | 0.87 | ABCC9 (0.37) | IDO1ABCC9 | |
| SCHEMBL482676 | 0.87 | ABCC9 (0.37) | IDO1ABCC9 | |
| SCHEMBL482485 | 0.87 | ABCC9 (0.37) | IDO1ABCC9 | |
| SCHEMBL7762928 | 0.81 | — | — | |
| SCHEMBL8071529 | 0.78 | ABCB1 (0.33) | ABCC9 | |
| SCHEMBL7770957 | 0.76 | AR (0.35) | IDO1 | |
| SCHEMBL482484 | 0.74 | KCNE1 (0.47) | ABCC9 | |
| SCHEMBL7258587 | 0.74 | KCNE1 (0.38) | IDO1ABCC9 | |
| SCHEMBL8060714 | 0.74 | ABCC9 (0.36) | KDM1AKDM1BAKR1B1ABCC9 | |
| SCHEMBL8060716 | 0.74 | ABCC9 (0.36) | KDM1AKDM1BAKR1B1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071953-A | Sulfonamide-substituted chromans, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-06-06 | — | — | US | disclosed |
| CN-1194982-A | Sulfonamide-substituted chromans, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them | HOECHST AG (DE) | 1998-10-07 | — | — | CN | disclosed |
| EP-0860440-A1 | Sulfonamido substituted chromane derivatives with potassium channel blocking activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-26 | — | — | EP | disclosed |