SCHEMBL7770957

SCHEMBL7770957

CC1(C)Oc2cc(F)c(C(F)(F)F)cc2[C@H]2O[C@H]21

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.35
IDO1 P14902 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7762928 0.84
SCHEMBL8069749 0.76 KDM1A (0.33) IDO1
SCHEMBL9753193 0.75 TRPV1 (0.36) IDO1
SCHEMBL7768331 0.75 CYP1A2 (0.37) IDO1
SCHEMBL482485 0.71 ABCC9 (0.37) IDO1
SCHEMBL482676 0.71 ABCC9 (0.37) IDO1
SCHEMBL7874514 0.71 IDO1 (0.33) IDO1
SCHEMBL7766754 0.71 IDO1 (0.30) IDO1
SCHEMBL9753241 0.70 IDO1 (0.34) ARIDO1
SCHEMBL7870442 0.69 KCNE1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1109801-A1 SUBSTITUTED DIHYDROBENZOPYRANS USEFUL AS ANTIARRHYTHMIC AGENTS THE PROCTER & GAMBLE COMPANY (US) 2001-06-27 EP disclosed
WO-2000014084-A1 SUBSTITUTED DIHYDROBENZOPYRANS USEFUL AS ANTIARRHYTHMIC AGENTS THE PROCTER & GAMBLE COMPANY (US) 2000-03-16 WO disclosed