Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874469 | 0.82 | CHRNA7 (0.66) | CA9CHRNA7PTGS2 | |
| SCHEMBL8067397 | 0.82 | CA9 (0.48) | CA9CHRNA7KMT2AMEN1TP53 | |
| SCHEMBL7872741 | 0.74 | CHRNA7 (0.66) | CA9CHRNA7PTGS2 | |
| SCHEMBL8633828 | 0.74 | CA9 (0.77) | CA9CHRNA7PTGS2PTGS1 | |
| SCHEMBL1764921 | 0.73 | TP53 (0.57) | CA9CHRNA7KMT2ATP53MAPT | |
| SCHEMBL7874475 | 0.72 | CHRNA7 (0.63) | CA9CHRNA7PTGS2PTGS1 | |
| SCHEMBL2195530 | 0.72 | LMNA (0.56) | CA9CHRNA7KMT2ATP53GAA | |
| SCHEMBL9941326 | 0.72 | CA9 (0.82) | CA9CHRNA7PTGS2PTGS1 | |
| SCHEMBL8075050 | 0.71 | F10 (0.41) | KMT2AMEN1PTGS2PTGS1 | |
| SCHEMBL7876242 | 0.71 | CA9 (0.66) | CA9CHRNA7PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017678-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015505-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |