Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 7/20 | 1.00 |
| ▸ | TRPC6 | Q9Y210 | 7/20 | 1.00 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.55 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806807 | 0.82 | TRPC3 (0.69) | TRPC3TRPC6TRPV1TRPA1CACNA1C | |
| SCHEMBL10080527 | 0.80 | TRPC3 (0.66) | TRPC3TRPC6TRPV1TRPA1CACNA1C | |
| SCHEMBL790044 | 0.78 | TRPC3 (0.71) | TRPC3TRPC6TRPV1TRPA1CACNA1C | |
| SCHEMBL10080530 | 0.78 | TRPC3 (0.63) | TRPC3TRPC6TRPV1TRPA1CACNA1C | |
| SCHEMBL807009 | 0.77 | TRPC3 (0.69) | TRPC3TRPC6MAPTRIPK1KDR | |
| SCHEMBL807012 | 0.76 | TRPC3 (0.62) | TRPC3TRPC6TRPV1TRPA1CACNA1C | |
| SCHEMBL790188 | 0.75 | TRPC3 (0.72) | TRPC3TRPC6TRPV1TRPA1CACNA1C | |
| SCHEMBL26459144 | 0.75 | TRPC3 (0.72) | TRPC3TRPC6TRPV1TRPA1CACNA1C | |
| SCHEMBL807016 | 0.74 | TRPC3 (0.58) | TRPC3TRPC6TRPV1TRPA1CACNA1C | |
| SCHEMBL10080531 | 0.74 | TRPC3 (0.58) | TRPC3TRPC6CNR1CNR2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037349-A2 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |