Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446360 | 0.86 | TSHR (0.45) | ALDH1A1TDP1MEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL8068543 | 0.86 | TSHR (0.45) | ALDH1A1TDP1MEN1POLBKMT2A | |
| SCHEMBL8059458 | 0.81 | GPBAR1 (0.50) | — | |
| SCHEMBL8073882 | 0.81 | GAA (0.39) | ALDH1A1POLBMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8446364 | 0.80 | CA1 (0.55) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL8059524 | 0.78 | KDM4E (0.50) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL8070783 | 0.77 | PTPN1 (0.44) | ALDH1A1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL7995261 | 0.76 | TTR (0.61) | ALDH1A1TDP1POLBNPSR1 | |
| SCHEMBL8073502 | 0.75 | TTR (0.51) | ALDH1A1POLBMAPTNPSR1 | |
| SCHEMBL8068695 | 0.74 | ADRA1A (0.42) | POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |