Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8059371 | 0.86 | KDM4E (0.41) | KDM4EMAPTSYKP2RX4MEN1 | |
| SCHEMBL8070554 | 0.84 | PKM (0.46) | KDM4EMAPTPKMP2RX4MEN1 | |
| SCHEMBL8059512 | 0.78 | PKM (0.50) | MAPTPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL8070492 | 0.77 | PKM (0.46) | KDM4EMAPTPKMP2RX4MEN1 | |
| SCHEMBL8068473 | 0.76 | TBXAS1 (0.55) | KDM4EPKMMEN1KMT2AALDH1A1 | |
| Diethylamine SCHEMBL8068847 | 0.76 | PKM (0.52) | KDM4EMAPTPKMP2RX4MEN1 | |
| SCHEMBL8059524 | 0.75 | KDM4E (0.50) | KDM4EMAPTSYKAURKBINCENP | |
| SCHEMBL8070495 | 0.75 | KDM4E (0.67) | KDM4EMAPTPKMALDH1A1GAA | |
| SCHEMBL8171561 | 0.74 | PKM (0.47) | KDM4EMAPTPKMMEN1KMT2A | |
| Morpholine SCHEMBL8068472 | 0.73 | PKM (0.46) | PKMALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |