Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8059489 | 0.86 | CA1 (0.34) | PKMMAPTKDM4ECA1CA2 | |
| SCHEMBL8070490 | 0.84 | KDM4E (0.52) | PKMMAPTKDM4ECA2TDP1 | |
| SCHEMBL8059512 | 0.77 | PKM (0.50) | PKMMAPTTHRATHRBCA1 | |
| SCHEMBL8068473 | 0.75 | TBXAS1 (0.55) | PKMKDM4ECA1CA2CA9 | |
| SCHEMBL8070556 | 0.75 | MAPT (0.47) | PKMMAPTKDM4EHTTTDP1 | |
| Diethylamine SCHEMBL8068847 | 0.75 | PKM (0.52) | PKMMAPTKDM4ETHRATHRB | |
| Morpholine SCHEMBL8068472 | 0.74 | PKM (0.46) | PKMTHRATHRBTDP1POLB | |
| Piperidine SCHEMBL8073727 | 0.74 | PKM (0.48) | PKMKDM4ETHRATHRBCA2 | |
| SCHEMBL1473732 | 0.71 | ALDH1A1 (0.42) | MAPTPOLBALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8059371 | 0.71 | KDM4E (0.41) | MAPTKDM4ECA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |