Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.43 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447053 | 0.88 | CYP19A1 (0.43) | CYP19A1CYP51A1 | |
| Hydrochloric Acid SCHEMBL8059719 | 0.87 | CYP19A1 (0.42) | CYP19A1CYP51A1 | |
| SCHEMBL8059431 | 0.84 | CYP19A1 (0.51) | CYP19A1CYP51A1TBXAS1MEN1LMNA | |
| SCHEMBL8068480 | 0.79 | CYP19A1 (0.55) | CYP19A1TBXAS1KMT2A | |
| SCHEMBL8073502 | 0.75 | TTR (0.51) | — | |
| SCHEMBL8070681 | 0.75 | MAPT (0.42) | MEN1LMNAKMT2A | |
| SCHEMBL8070558 | 0.74 | CYP24A1 (0.39) | KMT2A | |
| SCHEMBL11263221 | 0.73 | CYP19A1 (0.63) | CYP19A1CYP51A1HMOX1 | |
| SCHEMBL11274680 | 0.73 | CYP19A1 (0.63) | CYP19A1CYP51A1HMOX1TBXAS1 | |
| SCHEMBL8068490 | 0.73 | TTR (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |