Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446065 | 0.88 | CYP19A1 (0.50) | CYP19A1ALDH1A1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL8070594 | 0.87 | CYP19A1 (0.49) | CYP19A1ALDH1A1POLBKMT2A | |
| SCHEMBL8059431 | 0.81 | CYP19A1 (0.51) | CYP19A1TBXAS1KMT2A | |
| SCHEMBL8070529 | 0.79 | CYP19A1 (0.45) | CYP19A1TBXAS1KMT2A | |
| SCHEMBL8068849 | 0.78 | ALDH1A1 (0.54) | ALDH1A1POLBKMT2A | |
| SCHEMBL8070558 | 0.78 | CYP24A1 (0.39) | ALDH1A1KMT2A | |
| SCHEMBL8068934 | 0.78 | SIGMAR1 (0.51) | POLBKMT2A | |
| SCHEMBL5564831 | 0.77 | ALDH1A1 (0.74) | CYP19A1ALDH1A1POLBTBXAS1KMT2A | |
| SCHEMBL8073771 | 0.76 | KMT2A (0.58) | ALDH1A1POLBKMT2A | |
| SCHEMBL8070495 | 0.76 | KDM4E (0.67) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |