Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447165 | 0.78 | NPSR1 (0.45) | GFERNPSR1ALDH1A1TDP1 | |
| SCHEMBL8068480 | 0.78 | CYP19A1 (0.55) | ALDH1A1KMT2A | |
| SCHEMBL8059431 | 0.75 | CYP19A1 (0.51) | KMT2ATDP1 | |
| SCHEMBL8070529 | 0.74 | CYP19A1 (0.45) | KMT2A | |
| SCHEMBL8068476 | 0.74 | CYP17A1 (0.45) | CYP24A1CYP3A4 | |
| SCHEMBL8446010 | 0.73 | MAPT (0.42) | NPSR1ALDH1A1KMT2A | |
| SCHEMBL8059678 | 0.73 | NPSR1 (0.44) | NPSR1ALDH1A1KMT2A | |
| SCHEMBL8059681 | 0.72 | TTR (0.45) | GFERNPSR1GAA | |
| SCHEMBL8068849 | 0.72 | ALDH1A1 (0.54) | GFERALDH1A1KMT2ATDP1 | |
| SCHEMBL8073502 | 0.72 | TTR (0.51) | NPSR1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |