Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075407 | 0.96 | PPARA (0.36) | PPARAKDM4ERIPK1EDNRBEDNRA | |
| SCHEMBL8070835 | 0.86 | EDNRB (0.33) | KDM4ERIPK1EDNRBEDNRAKIF11 | |
| SCHEMBL8071089 | 0.86 | EDNRB (0.33) | KDM4ERIPK1EDNRBEDNRAKIF11 | |
| SCHEMBL702654 | 0.74 | RIPK1 (0.34) | PPARARIPK1LTB4R | |
| SCHEMBL5079143 | 0.72 | PPARA (0.39) | PPARAKDM4ELTB4RALDH1A1 | |
| SCHEMBL4528482 | 0.71 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL2556823 | 0.70 | EDNRB (0.33) | PPARAKDM4ERIPK1EDNRBEDNRA | |
| SCHEMBL5073221 | 0.69 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL706844 | 0.69 | RIPK1 (0.35) | PPARARIPK1 | |
| SCHEMBL8629910 | 0.68 | MME (0.32) | PPARAKDM4EGRNSORT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080771-A | LEINAMYCIN DERIVATIVES ARE USED AS BACTERICIDE AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0887351-A1 | DC 107 DERIVATIVES (2) | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-12-30 | — | — | EP | disclosed |