Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071089 | 1.00 | EDNRB (0.33) | EDNRBEDNRAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8075407 | 0.87 | PPARA (0.36) | EDNRBEDNRAALDH1A1KDM4ERIPK1 | |
| SCHEMBL8070765 | 0.86 | PPARA (0.33) | EDNRBEDNRAALDH1A1KDM4ERIPK1 | |
| SCHEMBL2556823 | 0.82 | EDNRB (0.33) | EDNRBEDNRAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL708400 | 0.67 | RIPK1 (0.37) | RIPK1MAPK1 | |
| SCHEMBL8629910 | 0.67 | MME (0.32) | ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL9802325 | 0.67 | ATM (0.37) | EDNRBEDNRAALDH1A1GAATDP1 | |
| SCHEMBL4528482 | 0.65 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL9736778 | 0.65 | ADRB2 (0.32) | — | |
| SCHEMBL8559419 | 0.64 | RIPK1 (0.43) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080771-A | LEINAMYCIN DERIVATIVES ARE USED AS BACTERICIDE AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0887351-A1 | DC 107 DERIVATIVES (2) | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-12-30 | — | — | EP | disclosed |