Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.60 |
| ▸ | TSHR | P16473 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30733854 | 1.00 | HSD17B10 (0.60) | HSD17B10TSHRHPGDAHRCYP3A4 | |
| SCHEMBL305189 | 0.89 | TSHR (0.60) | HSD17B10TSHRHPGDAHRCYP3A4 | |
| SCHEMBL29720512 | 0.89 | TSHR (0.60) | HSD17B10TSHRHPGDAHRCYP3A4 | |
| SCHEMBL2215984 | 0.86 | TSHR (0.57) | HSD17B10TSHRHPGDAHRCYP3A4 | |
| SCHEMBL8820666 | 0.86 | TSHR (0.57) | HSD17B10TSHRHPGDAHRCYP3A4 | |
| Triclofenol SCHEMBL11818770 | 0.80 | HSD17B10 (0.64) | HSD17B10TSHRHPGDAHRCYP3A4 | |
| SCHEMBL69259 | 0.78 | HSD17B10 (0.80) | HSD17B10TSHRHPGDAHRCYP3A4 | |
| SCHEMBL11282194 | 0.78 | AHR (0.55) | HSD17B10TSHRHPGDAHRCYP3A4 | |
| SCHEMBL8640677 | 0.78 | TSHR (0.52) | HSD17B10TSHRHPGDAHRCYP3A4 | |
| SCHEMBL31376053 | 0.77 | TSHR (0.46) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344240-A | Preparation method of 2, 4-dichloro-5-bromophenol | 中国科学技术大学 | 2024-07-16 | — | — | CN | claimed |
| US-12133529-B2 | Herbicidal phenylethers | BASF SE (DE) | 2024-11-05 | — | — | US | disclosed |
| CN-118344240-A | Preparation method of 2, 4-dichloro-5-bromophenol | 中国科学技术大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-118344240-A | Preparation method of 2, 4-dichloro-5-bromophenol | 中国科学技术大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-118344240-A | Preparation method of 2, 4-dichloro-5-bromophenol | 中国科学技术大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-117466714-A | Preparation method of 2, 4-dichloro-5-halogenated phenol | 中国科学技术大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-117466714-A | Preparation method of 2, 4-dichloro-5-halogenated phenol | 中国科学技术大学 | 2024-01-30 | — | — | CN | disclosed |
| US-20230345941-A1 | HERBICIDAL PHENYLETHERS | BASF SE (DE) | 2023-11-02 | — | — | US | disclosed |
| CN-115151532-B | Quinoxalindione derivatives as irreversible inhibitors of KRAS G12C muteins | 北京泰德制药股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-115151532-A | Quinoxalinedione derivatives as irreversible inhibitors of KRAS G12C muteins | 北京泰德制药股份有限公司 | 2022-10-04 | — | — | CN | disclosed |
| WO-2021219090-A1 | QUINOXALINE DIONE DERIVATIVE AS IRREVERSIBLE INHIBITOR OF KRAS G12C MUTANT PROTEIN | 北京泰德制药股份有限公司 (CN) | 2021-11-04 | — | — | WO | disclosed |
| US-20200305429-A1 | HERBICIDAL PHENYLETHERS | BASF SE (DE) | 2020-10-01 | — | — | US | disclosed |
| CN-111356693-A | Herbicidal phenyl ethers | 巴斯夫欧洲公司 | 2020-06-30 | — | — | CN | disclosed |
| WO-2019101551-A1 | HERBICIDAL PHENYLETHERS | BASF SE (DE) | 2019-05-31 | — | — | WO | disclosed |
| EP-0821688-B1 | NOVEL BETA-METHOXY ACRYLIC ACID DERIVATIVES, METHOD FOR PREPARING SAME, AND USE OF SAID DERIVATIVES AS PESTICIDES | HOECHST SCHERING AGREVO SA (FR) | 2000-07-26 | — | — | EP | disclosed |
| US-5985853-A | β-methoxy acrylic acid derivatives, method for preparing same, and use of said derivatives as pesticides | HOECHST MARION ROUSSEL (FR) | 1999-11-16 | — | — | US | disclosed |
| CN-1181757-A | Novel 'beta'-methoxy acrylic acid derivatives, method for preparing same, and use of said derivatives as pesticides | HOECHST SCHERING AGREVO SA (FR) | 1998-05-13 | — | — | CN | disclosed |
| EP-0821688-A1 | NOVEL $g(b)-METHOXY ACRYLIC ACID DERIVATIVES, METHOD FOR PREPARING SAME, AND USE OF SAID DERIVATIVES AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996032399-A1 | NOVEL β-METHOXY ACRYLIC ACID DERIVATIVES, METHOD FOR PREPARING SAME, AND USE OF SAID DERIVATIVES AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1996-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200305429-A1 | HERBICIDAL PHENYLETHERS | DDT, HPD, GSTM2 | HSD17B10 110/4885TSHR 3222/4885HPGD 1220/4885 |
| US-12133529-B2 | Herbicidal phenylethers | DDT, HPD, GSTM2 | HSD17B10 110/4885TSHR 3222/4885HPGD 1220/4885 |
| US-20230345941-A1 | HERBICIDAL PHENYLETHERS | DDT, HPD, GSTM2 | HSD17B10 110/4885TSHR 3222/4885HPGD 1220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.