Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | CA4 | P22748 | 2/20 | 0.62 |
| ▸ | CA6 | P23280 | 2/20 | 0.62 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29540971 | 1.00 | CA1 (0.62) | CA1CA2CA4CA6PLCG1 | |
| Pyridine SCHEMBL6698276 | 0.86 | CA1 (0.48) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL6294222 | 0.82 | CA1 (0.48) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL841244 | 0.81 | CA2 (0.46) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL250199 | 0.81 | ALDH1A1 (0.55) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL25294557 | 0.79 | CA2 (0.45) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL31152920 | 0.79 | CA2 (0.45) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL38660050 | 0.79 | CA1 (0.68) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL2475835 | 0.79 | CA1 (0.68) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL11521127 | 0.78 | CA2 (0.52) | CA1CA2CA4CA6PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119425423-A | Positively charged composite membrane and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-117603097-B | Method for rapidly preparing 2-bromo-5-nitrobenzenesulfonyl chloride | 安徽泽升科技股份有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-117924290-A | Preparation method and application of long-life organic room-temperature phosphorescent material of filter paper matrix | 天津理工大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117603097-A | Method for rapidly preparing 2-bromo-5-nitrobenzenesulfonyl chloride | 安徽泽升科技股份有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117551005-A | Synthesis method of 2-bromobenzenesulfonyl chloride and derivatives thereof | 常州锐博生物科技有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-115181100-A | Sulfonamide micromolecule inhibitor with purine and pyrrolopyrimidine parent nucleus | 广西大学 | 2022-10-14 | — | — | CN | claimed |
| CN-111675716-B | Fangchinoline derivative with anticancer activity and preparation method and application thereof | 山东省农业科学院农产品研究所 | 2022-09-13 | — | — | CN | claimed |
| CN-217313437-U | Continuous production system of 2-bromobenzene sulfonyl chloride | 常州锐博生物科技有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-113185435-A | Method for preparing beta-carbonyl sulfone compound by using half-sandwich iridium complex | 上海应用技术大学 | 2021-07-30 | — | — | CN | claimed |
| CN-108727224-B | Process for preparing intermediates for the synthesis of pharmaceuticals | 株式会社LG化学 | 2021-03-23 | — | — | CN | claimed |
| EP-1328523-A2 | METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES | Bristol-Myers Squibb Company (US) | 2003-07-23 | — | — | EP | claimed |
| US-20020132838-A1 | Methods for the preparation of biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-19 | — | — | US | claimed |
| WO-2002032884-A2 | METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-04-25 | — | — | WO | claimed |
| EP-0904077-A4 | METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL MYERS SQUIBB CO (US) | 1999-12-22 | — | — | EP | claimed |
| EP-0904077-A2 | METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-31 | — | — | EP | claimed |
| CN-1211183-A | Methods for preparation of biphenyl isoxazole sulfonamides | BRISTOL MYERS SQUIBB CO (US) | 1999-03-17 | — | — | CN | claimed |
| EP-0576229-B1 | Low temperature process for preparing alpha-anomer enriched 2-deoxy-2, 2-difluoro-D-ribofuranosyl sulfonates | LILLY CO ELI (US) | 1997-12-17 | — | — | EP | claimed |
| WO-1997029747-A1 | METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-08-21 | — | — | WO | claimed |
| US-5401861-A | CONTACTING A LACTOL WITH AN AMINE BASE, COOLING AND ADDING A SULFONATING REAGENT | ELI LILLY AND COMPANY (US) | 1995-03-28 | — | — | US | claimed |
| EP-0576229-A1 | Low temperature process for preparing alpha-anomer enriched 2-deoxy-2, 2-difluoro-D-ribofuranosyl sulfonates | ELI LILLY AND COMPANY (US) | 1993-12-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020132838-A1 | Methods for the preparation of biphenyl isoxazole sulfonamides | REN, STS, CYP4X1 | CA1 2974/4885CA2 602/4885CA4 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.