Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068448 | 0.83 | GABRA1 (0.49) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL12117486 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HSD17B10CFTRHPGDMAPT | |
| SCHEMBL27717289 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HSD17B10CFTRHPGDMAPT | |
| SCHEMBL16419694 | 0.80 | GABRA1 (0.55) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL8059705 | 0.78 | CFTR (0.53) | ALDH1A1CFTRHPGDMAPTMEN1 | |
| SCHEMBL8608047 | 0.78 | PTGS2 (0.52) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL1720999 | 0.78 | KDM4E (0.56) | ALDH1A1HSD17B10CFTRHPGDMAPT | |
| SCHEMBL23628969 | 0.78 | PTGS2 (0.58) | ALDH1A1HSD17B10CFTRHPGDMAPT | |
| SCHEMBL2686505 | 0.78 | EGFR (0.61) | ALDH1A1HSD17B10HPGDMAPTMEN1 | |
| SCHEMBL5799055 | 0.77 | PTGS2 (0.48) | ALDH1A1HSD17B10CFTRHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |