Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067216 | 0.89 | PNP (0.36) | ALDH1A1HTT | |
| SCHEMBL8069285 | 0.87 | ALDH1A1 (0.34) | MEN1KMT2ATDP1ALDH1A1PDE3B | |
| SCHEMBL8067201 | 0.87 | MEN1 (0.35) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL8071853 | 0.83 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL8555615 | 0.82 | KDM4E (0.33) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL12829055 | 0.82 | MAOB (0.36) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL6087128 | 0.80 | TPH1 (0.34) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL8069190 | 0.78 | KMT2A (0.44) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL1484944 | 0.78 | PDE3B (0.31) | PDE3BPDE3A | |
| SCHEMBL6087134 | 0.78 | MEN1 (0.32) | MEN1KMT2ATDP1HTTPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136815-A | VIRICIDES FOR TREATMENT OF AIDS | KOREA RESEARCH INST. OF CHEM. TECH. (KR) | 2000-10-24 | — | — | US | disclosed |