Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076863 | 0.88 | ALDH1A1 (0.50) | LMNAPOLBMAPTGFERNPSR1 | |
| SCHEMBL8071856 | 0.79 | MGLL (0.47) | LMNAPOLBMAPTALDH1A1 | |
| SCHEMBL15920285 | 0.72 | NPY2R (0.49) | LMNAPOLBMAPTGFERNPSR1 | |
| SCHEMBL5208408 | 0.72 | MEN1 (0.56) | LMNAPOLBMAPTGFERNPSR1 | |
| SCHEMBL8061122 | 0.71 | HDAC1 (0.47) | MAPTFLT3ALDH1A1 | |
| SCHEMBL4087324 | 0.70 | HTR2B (0.53) | LMNAPOLBMAPTALDH1A1 | |
| SCHEMBL8070244 | 0.70 | EHMT2 (0.52) | — | |
| SCHEMBL1192635 | 0.70 | EGLN1 (0.83) | EGLN1 | |
| SCHEMBL1664788 | 0.70 | CHEK2 (0.68) | LMNAPOLBMAPTGFERALDH1A1 | |
| SCHEMBL10383149 | 0.69 | KCNH2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156758-A | Antibacterial quinazoline compounds | ISIS PHARMACEUTICALS, INC. (US) | 2000-12-05 | — | — | US | disclosed |