Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 12/20 | 0.52 |
| ▸ | EHMT1 | Q9H9B1 | 5/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | WHR1 | P49842 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071911 | 0.89 | ADRA1A (0.62) | ADRA1AADRA1B | |
| SCHEMBL8061075 | 0.88 | EHMT2 (0.48) | EHMT2EHMT1ADRA1AADRA1BWHR1 | |
| SCHEMBL8070283 | 0.85 | CCR4 (0.56) | EHMT2EHMT1WHR1 | |
| SCHEMBL8061122 | 0.83 | HDAC1 (0.47) | EHMT2EHMT1ADRA1AADRA1B | |
| SCHEMBL8071856 | 0.82 | MGLL (0.47) | EHMT2EHMT1 | |
| SCHEMBL8077026 | 0.82 | ADRA1A (0.60) | ADRA1AADRA1B | |
| SCHEMBL8076826 | 0.78 | ADRA1A (0.56) | ADRA1AADRA1B | |
| SCHEMBL8071748 | 0.77 | ADRA1A (0.60) | ADRA1AADRA1B | |
| SCHEMBL8070274 | 0.75 | CCR4 (0.52) | EHMT2EHMT1WHR1 | |
| SCHEMBL8071975 | 0.74 | ADRA1A (0.56) | ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156758-A | Antibacterial quinazoline compounds | ISIS PHARMACEUTICALS, INC. (US) | 2000-12-05 | — | — | US | disclosed |