SCHEMBL8071874

SCHEMBL8071874

COC1CCOc2c(SC)cc(C(=O)CC(=O)C3CC3)c(Cl)c21

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8070198 0.74 ALDH1A1 (0.33) TSHR
SCHEMBL8071872 0.70
SCHEMBL6748543 0.67 ERCC5 (0.39)
SCHEMBL9073271 0.66 MAPT (0.35)
SCHEMBL8307791 0.65 TSHR (0.34) TSHR
SCHEMBL8308747 0.65 HSD17B10 (0.33)
SCHEMBL8310642 0.65 HSD17B10 (0.33)
SCHEMBL8400560 0.63 TSHR (0.32) TSHR
SCHEMBL8134513 0.63 KDM4E (0.33) TSHR
SCHEMBL6746643 0.62 ERCC5 (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6037312-A HERBICIDES IDEMITSU KOSAN CO., LTD. (JP) 2000-03-14 US disclosed