Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8813179 | 0.83 | SLC6A4 (0.45) | MEN1KMT2ASLC6A4SLC6A2P2RX7 | |
| SCHEMBL9069942 | 0.82 | DRD2 (0.39) | MAPTSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL6748543 | 0.80 | ERCC5 (0.39) | MAPTSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL8494921 | 0.78 | SMN1; SMN2 (0.35) | MAPTSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL7550426 | 0.77 | ALDH1A1 (0.33) | MAPTALDH1A1KMT2AGAALMNA | |
| SCHEMBL6746643 | 0.77 | ERCC5 (0.36) | MAPTSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL8389663 | 0.75 | SMN1; SMN2 (0.36) | MAPTSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL7574482 | 0.73 | HPGD (0.33) | SMN1; SMN2ALDH1A1HPGDKMT2AP2RX7 | |
| SCHEMBL3773890 | 0.73 | TSHR (0.37) | MAPTSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL30978700 | 0.73 | TSHR (0.37) | MAPTSMN1; SMN2ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527037-B1 | 4-Benzoylisoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-10-16 | — | — | EP | disclosed |
| EP-0527037-A1 | 4-Benzoylisoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-02-10 | — | — | EP | disclosed |