Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622748 | 0.84 | GSK3B (0.47) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL4616213 | 0.84 | GSK3B (0.50) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL4617244 | 0.79 | CA12 (0.67) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL4616586 | 0.76 | ADORA3 (0.48) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL5708551 | 0.76 | KMT2A (0.59) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL8071998 | 0.75 | CA12 (0.63) | CA12CA1CA2PTGS2CA9 | |
| SCHEMBL5281877 | 0.75 | KMT2A (0.65) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL5708549 | 0.75 | KMT2A (0.61) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL31217446 | 0.74 | KMT2A (0.98) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL11043352 | 0.74 | KMT2A (0.48) | KMT2AMEN1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429274-B2 | Agent and method for the oxidative coloring of keratin fibers | WELLA AG (DE) | 2008-09-30 | — | — | US | claimed |
| EP-1601335-B1 | MEANS AND METHOD FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES | WELLA AG (DE) | 2008-03-19 | — | — | EP | claimed |
| EP-1699427-B1 | AGENT AND METHOD FOR OXIDATIVELY DYING KERATIN FIBERS | WELLA AG (DE) | 2008-02-27 | — | — | EP | claimed |
| US-7326254-B2 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | WELLA AG (DE) | 2008-02-05 | — | — | US | claimed |
| EP-1599178-B1 | MEANS AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2007-12-19 | — | — | EP | claimed |
| US-7291183-B2 | Agent and method for dyeing keratin fibers | WELLA AG (DE) | 2007-11-06 | — | — | US | claimed |
| US-7244278-B2 | Agent and method for oxidative coloring of keratin fibers | WELLA AG (DE) | 2007-07-17 | — | — | US | claimed |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | Wella GmbH (DE) | 2007-04-12 | — | — | US | claimed |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2007-03-29 | — | — | US | claimed |
| EP-1754514-A1 | Agent and method for colouring keratin fibres | Wella Aktiengesellschaft (DE) | 2007-02-21 | — | — | EP | claimed |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | claimed |
| EP-1599179-B1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | claimed |
| EP-1699426-A1 | AGENT AND METHOD FOR OXIDATIVELY DYEING KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2006-09-13 | — | — | EP | claimed |
| WO-2006094217-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-08 | — | — | WO | claimed |
| US-20060162096-A1 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2006-07-27 | — | — | US | claimed |
| US-20060010616-A1 | Agent and method for dyeing keratin fibers | Wella GmbH (DE) | 2006-01-19 | — | — | US | claimed |
| WO-2005060927-A1 | AGENT AND METHOD FOR OXIDATIVELY DYEING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-07 | — | — | WO | claimed |
| US-7429274-B2 | Agent and method for the oxidative coloring of keratin fibers | WELLA AG (DE) | 2008-09-30 | — | — | US | disclosed |
| US-20060162096-A1 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2006-07-27 | — | — | US | disclosed |
| US-20060010616-A1 | Agent and method for dyeing keratin fibers | Wella GmbH (DE) | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060162096-A1 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | KRT18, GPX4, NOX4 | KMT2A 645/4885MEN1 3146/4885CA12 203/4885 |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | KRT18, KIT, AOC1 | KMT2A 751/4885MEN1 3495/4885CA12 332/4885 |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | KRT18, CDC73, OAT | KMT2A 1376/4885MEN1 3258/4885CA12 354/4885 |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | KRT18, KIT, CKMT1A; CKMT1B | KMT2A 1187/4885MEN1 3980/4885CA12 266/4885 |
| US-20060010616-A1 | Agent and method for dyeing keratin fibers | KRT18, KIT, MKI67 | KMT2A 1345/4885MEN1 4224/4885CA12 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.