SCHEMBL8072013

SCHEMBL8072013

CCOC(=O)c1cc(SC)c2c(c1Cl)C(OC)CCO2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
NPSR1 Q6W5P4 3/20 0.37
KDM4E B2RXH2 2/20 0.37
TSHR P16473 2/20 0.36
LMNA P02545 2/20 0.36
HPGD P15428 3/20 0.35
HSD17B10 Q99714 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
HTR4 Q13639 2/20 0.33
MAPT P10636 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
HIF1A Q16665 1/20 0.33
HTR2C P28335 2/20 0.32
HTR3A P46098 2/20 0.32
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8071874 0.81 TSHR (0.32) TSHR
SCHEMBL8405173 0.80 KDM4E (0.32) ALDH1A1NPSR1KDM4ETSHRLMNA
SCHEMBL8134482 0.74 FUCA1 (0.36) ALDH1A1NPSR1KDM4ETSHRHPGD
SCHEMBL8133198 0.74 NPSR1 (0.37) ALDH1A1NPSR1KDM4ETSHRLMNA
SCHEMBL6721449 0.71 ADORA3 (0.40) ALDH1A1NPSR1KDM4ELMNAHPGD
SCHEMBL8307791 0.71 TSHR (0.34) TSHRMEN1KMT2A
SCHEMBL8072009 0.70 ALDH1A1 (0.35) ALDH1A1NPSR1KDM4ETSHRCA1
SCHEMBL8135015 0.68 NPSR1 (0.37) ALDH1A1NPSR1KDM4ETSHRLMNA
SCHEMBL8405209 0.67 MAOB (0.36) ALDH1A1NPSR1KDM4ETSHRLMNA
SCHEMBL8400560 0.65 TSHR (0.32) TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6037312-A HERBICIDES IDEMITSU KOSAN CO., LTD. (JP) 2000-03-14 US disclosed